Number of shares in issue

As at 29 July 2019 the Company has 303,309,707 Ordinary shares of £0.00001 each in issue and no shares are held in treasury. The following interests of shareholders in excess of 3% have been notified to the Company.

Significant shareholders
Manager Origin Holdings %
Invesco Perpetual  UK 88,670,000 29.2
Woodford Investment Management UK 60,630,350 20.0
Forward Innovation Fund UK 34,072,336 11.2
Forward Nominees Limited UK 16,481,456 5.4
NFU UK 13,860,000 4.6
Baillie Gifford UK 11,567,100 3.8

In accordance with the AIM Rule 26 in so far as the Company is aware, as at 29 July 2019 the percentage of the Company’s issued share capital that is not in public hands is 71.8%.

Details of any restrictions on the transfer of securities - There are no restrictions on the transfer of securities.

Details of any other exchange or trading platforms - The Company operates on no other exchanges or trading platforms other than AIM.