Number of shares in issue
As at 19 March 2020 the Company has 440,109,707 Ordinary shares of £0.00001 each in issue and no shares are held in treasury. The following interests of shareholders in excess of 3% have been notified to the Company.
| Significant shareholders | Origin | Holding | % |
| Invesco Limited | UK | 63,113,333 | 14.3 |
| Forward Innovation Fund | UK | 38,072,336 | 8.7 |
| Librae Holdings Limited | BVI | 28,208,528 | 6.4 |
| Forward Nominees Limited | UK | 22,631,208 | 5.1 |
| Ruffer LLP | UK | 22,088,000 | 5.0 |
| Investec Asset Management Limited | UK | 15,526,000 | 3.5 |
| The Hargreaves No 11 Settlement | UK | 14,000,000 | 3.2 |
In accordance with the AIM Rule 26 in so far as the Company is aware, as at 19 March 2020 the percentage of the Company’s issued share capital that is not in public hands is 30.9%.
Details of any restrictions on the transfer of securities - There are no restrictions on the transfer of securities.
Details of any other exchange or trading platforms - The Company operates on no other exchanges or trading platforms other than AIM.