Number of shares in issue

As at 30 June 2023 the Company has 446,581,202 Ordinary shares of £0.00001 each in issue and no shares are held in treasury. The following interests of shareholders holding 3% or more are as follows:

Significant shareholders Origin Holding %
Invesco Limited UK 63,113,333 14.1
Forward Innovation Fund UK 39,272,336 8.8
Ruffer LLP UK 30,300,000 6.8
Forward Nominees Limited UK 21,801,208 4.9
BlackRock UK 21,100,000 4.7
Chelverton Asset Management UK 20,000,000 4.5
Fidelity International UK 19,462,295 4.4
Columbia Threadneedle UK 18,087,919 4.1
GPIM UK 15,358,051 3.4
NVM Private Equity LLP UK 14,240,579 3.2
The Hargreaves No 11 Settlement UK 14,000,000 3.1


In accordance with the AIM Rule 26 in so far as the Company is aware, as at 30 June 2023 the percentage of the Company’s issued share capital that is not in public hands is 31.1%.

Details of any restrictions on the transfer of securities – There are no restrictions on the transfer of securities.

Details of any other exchange or trading platforms – The Company operates on no other exchanges or trading platforms other than AIM.