Number of shares in issue

As at 31 December 2023, the Company has 446,679,523 Ordinary shares of £0.00001 each in issue, with 2,840,069 of these shares currently held in treasury. Based upon the remainder of issued Ordinary shares not currently held in treasury, being 443,839,454, the following interests of shareholders holding 3.0% or more are as follows:

Significant shareholders Origin Holding %
Invesco Limited UK 63,113,333 14.2
Forward Innovation Fund UK 39,272,336 8.8
Fidelity International UK 38,644,338 8.7
Ruffer LLP UK 26,750,000 6.0
Forward Nominees Limited UK 21,801,208 4.9
Chelverton Asset Management UK 18,750,000 4.2
Columbia Threadneedle UK 18,074,309 4.1
GPIM UK 15,989,746 3.6
BlackRock UK 15,100,000 3.4
The Hargreaves No 11 Settlement UK 14,000,000 3.2
NFU Mutual UK 13,841,465 3.1


In accordance with AIM Rule 26 in so far as the Company is aware, as at 31 December 2023 the percentage of the Company’s issued share capital that is not in public hands is 31.3%.

Details of any restrictions on the transfer of securities – There are no restrictions on the transfer of securities.

Details of any other exchange or trading platforms – The Company operates on no other exchanges or trading platforms other than AIM.